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작성자 Lorie 작성일23-09-29 15:40 조회3회 댓글0건본문
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| Mesothelioma Caused by Asbestos Pleural mesothelioma is a condition where the lining of the lung the chest wall and belly (peritoneum) gets affected. About 90% of mesotheliomas develop at this site. Blood tests, X-rays and CT scans are able to help doctors detect fluid accumulation as well as signs of mesothelioma. A tissue biopsy is needed to confirm mesothelioma. Treatment options include chemotherapy, surgery and radiation. Asbestos Asbestos is a natural mineral composed of bundles of strong microscopic fibers. It was used to make various industrial and construction products from the 1930s through the 1980s. It is strong, fire-resistant, and tough. At the time non asbestos causes of mesothelioma was employed in many industries, including construction, shipbuilding, asbestos mining and other related areas. Asbestos exposure is usually inevitable, and occurs without the awareness of the risks. Inhaling asbestos fibers can lead to mesothelioma. They can then enter the lungs and travel to the lining of the chest cavity (pleura). The asbestos fibers irritate the pleura, leading to the formation of scar tissue. As time passes, this scar tissue can be transformed into malignant mesothelioma cancers. If the asbestos fibers are swallowed they may travel to the stomach and intestine. The asbestos fibers may irritate linings of the stomach or the intestines. This can cause mesothelioma grow in the peritoneum. Mesothelioma is more common for men than women and is generally found in people who are 65 years old or old or older. This is likely due to the fact that men were more likely to be employed in jobs that required asbestos and suffer from longer exposure. Mesothelioma is rare in children but can develop. Smoking and family history are additional factors that increase the risk of developing mesothelioma. The risk of mesothelioma in relatives of those suffering from the disease is a little higher, as they could have been exposed via secondary exposure to asbestos. Symptoms of mesothelioma often don't appear until decades after the first exposure to asbestos. The symptoms of mesothelioma can differ depending on the type of mesothelioma. The majority of patients with pleural cancer suffer from chest pain and a shortness of breathe. Some suffer from breathing difficulties and experience discomfort in their abdomen or throat. Asbestos varies in types, so it's important to see a specialist mesothelioma doctor who can determine the correct type of mesothelioma. They can suggest the best treatment for each patient. The best treatment is vital to improve the quality of life of patients and their chances of surviving. Silica Silica can be found in rocks, soil concrete, sand, and sand. Workers who use saws, drills or grinders to cut or grind these materials are exposed to silica dust from the air. The dust can cause lung disease and damage. Silica may also increase the risk of lung cancer, mesothelioma and other respiratory ailments. The silica crystal form (not to be confused with the amorphous silica) is a carcinogen, and it has been linked to a variety of autoimmune disorders. Silica can cause respiratory issues because it is abrasive and can tear and scrape the linings of respiratory passageways and nasal passageways. It could eventually lead to silicosis, a chronic fibrosing disease of the lungs, which could cause scarring that reduces the lungs' capacity to absorb oxygen. Silicosis can cause fatigue and difficulty breathing and make people more prone to infectious diseases, such as tuberculosis. Studies in animal models suggest that silica exposure leads to changes in the immune system of tumors. This is due to the creation of an immunosuppressive pulmonary microenvironment that encourages the growth of tumors. Silica exposure can increase macrophages, which causes them to release proinflammatory cytokines. One of the most important functions of macrophages, is that they are able to provide antigens and identify and eliminate neoplastic cells. It is important to determine if silica alters macrophages' capacity to perform this function by reducing their antigen-presenting capabilities and by modulating key immune functions when there is mesothelioma only caused by asbestos silica-induced altered tumor immunity. While the IARC has long acknowledged asbestos as a carcinogen it is not known whether silica could have similar effects on host immune system functions. The type of silica as well as the duration of exposure are crucial elements in the development of an immune response to the neoplasia. Since some studies have shown that the amount of Tregs in a host can be impacted in a manner that is able to reduce the tumor-killing ability, it is reasonable to expect the immunity against tumors in silica-exposed host to be diminished. Erionite Researchers have recently discovered that fibrous zeolite known as Erionite, which is one of the fibrous zeolite mineral, could also cause mesothelioma malignancy. The findings were published on July 25, 2011, in Proceedings of the National Academy of Sciences. Erionite is an igneous stone made up of silicon and aluminum that is found all over the world. It is mined to make raw materials and used in a variety industries, like glass and Refractory. Erionite can also be processed and sold as an aggregate for road construction and other projects. In the late 1970s, a high incidence pleural mesothelioma was found in villages in Cappadocia (Turkey) that were located near natural erionite deposits. Sarihidir and Karain were among the villages that were affected. The exposure to erionite has been responsible for a significant proportion of mesotheliomas that have been diagnosed in these villages. In 1981, the first case of lung disease caused by erionite North America was published. The man was an employee of a road in Utah near an erionite mine. A lung biopsy revealed extensive fibrosis in the pleura and parenchyma and the composition of lung tissue was determined by energy-dispersive-X-rays that were consistent with Erionite. In vitro studies have confirmed that erionite can cause cancer. It can cause mesothelioma if inhaled or intrapleurally injected. Erionite caused squamous-cell carcinoma in mice exposed to the mineral via their diet. In 2008, a mesothelioma group was discovered in a small village located in a region of zeolite richness of central Mexico. A mesothelioma victim in the same region was diagnosed with a pulmonary fibrosis that was extensive and pleural plaque and had an erionite lung load. Recent studies have focused on the occurrence of mesothelioma arising from erionite in s North Dakota and other areas where gravel pits extracted from erionite have been used to create roads and other infrastructure. Ambient and activity-based air testing was performed in these areas to identify mesothelioma caused by arsenic other causes (mouse click the up coming webpage) risk factors. The results indicated that erionite exposure is likely to be the cause of mesothelioma cases and it is suggested that the exposure be examined prior to any proposed relocation of affected villages. Chrysotile Chrysotile, commonly referred to as white asbestos, is the most common type of asbestos that is used. It is a serpentine material made up of magnesium and silica, [Redirect-302] with the formula: 3MgO*2SiO2*2H2O. It is found in three distinct forms: clinochrysotile orthochrysotile and parachrysotile. The differences between these three forms are due to the different interactions of oxygen atoms with the silicon tetrahedra and magnesium. These interactions affect the properties of the material, particularly its tensile strength and the way it interacts with water. Chrysotile, though asbestos in all forms are considered to be hazardous what is mesothelioma caused from only associated with mesothelioma or other diseases in instances where exposure was prolonged or high. This is due in part to the way it affects the human body. Chrysotile has less resistance to heat, and a greater affinity for fatty substances in the bloodstream. In the end, it tends to remain in the lungs for longer than other asbestos types, increasing its potential to cause illness. Additionally, chrysotile can be often found contaminated with the mineral tremolite, an amphibole. This makes it harder for the body to break down tremolite than it is to break down chrysotile. Health experts are still convinced that chrysotile poses a serious risk even though many groups are fighting to keep it in use. However it is vital to note that research on animals has demonstrated that even if chrysotile is exposed at a low level it is still able to cause mesothelioma and cancer. This is due to the fact that chrysotile could easily pass through lung tissues and get taken up by lymph nodes. However, the mesothelioma-related cases observed in the 11,000 Quebec chrysotile mine employees studied from 1992 onwards were mainly caused by tremolite exposure. The postmortem examinations of the lungs of miners revealed that cases were concentrated in certain areas of the lung. This suggests a strong connection to the tremolite. The only way to completely avoid mesothelioma is to eliminate all forms of asbestos. It should be eliminated from all products and any structures that were constructed using it should be cleaned to remove all traces of the substance. |
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이와 같이 수강신청서를 제출합니다. 불기 2569 (2025)년 12 월 18 일 신 청 자 Lorie (인) |
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